People: Bob Saget Said He Would Keep Fighting Scleroderma 'Until I'm Gone' in Interview Weeks Before Death Scleroderma causes areas of tight, hard skin, but can also harm your blood vessels and organs. Learn the causes and treatments of this skin disease. This program supports basic, translational, observational, and clinical studies on scleroderma, fibrosis, and autoinflammatory diseases.

Understanding the Context

Scleroderma is an autoimmune rheumatic disease without an available curative therapy. It is a heterogenous and complex disease that can be categorized as localized scleroderma (morphea) and systemic scleroderma.